A Lecture On Toxiocology: Delivered January 15, 1841, Before the Class of the Medical College of Ohio

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A local poison mav merely effect the contiguous nerves. It may irritate and inflame, or it may corrode and decompose. M. Robiqaet ascertained tiiat if the end of the finger be held over the end of a tube centaining Prussic acid, it became benumbed and remained so for more than a day.
M. Brodie mentions that when Monkshood is chewed it caus- es a sensation of tingling and numbness in the lips, lasting for hours. These are examples of effects produced locally on the nerves without any organic cha
...nge, not even redness.
The examples of local irritation and inflammation are nu- merous. Alcohol applied to the skin produces a transient redness, Cantharides, inflammation with vessication, Tar- tar emetic, a deeper inflammation followed by a pustular eruption. Arsenic, inflammatioM followed by ulceration and gangrene.
VVe have examples of external corrosion in the concentra- ted mineral acids and the caustic alkalies; and of intefixal ones in oxalic acid, lunar caustic, and corrosive sublimate.


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