A Manual of Physiology; for Students of Medicine

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From the nerve cell pass on a couple of filaments which pierce the various granu- lar and nuclear layers — where they probably freely inosculate with the fibrils from other cells — and finally terminate in a rod or a cone. The rods and cones may then be regarded as the ulti- mate terminals of the nerves, and they lie in the active proto- plasm of the peculiar, pigmented epithelium cells.
It is this outer layer, consisting of rods and cones lodged in epithelial protoplasm, which is the really ef
...fective part of the retina. Of this we have the following evidence: 1. The fact that the rods and cones must be regarded as the real anatomical nerve terminals of the optic nerve.
2. Where the optic nerve enters the eyeball and the nerve fibres are fully exposed to the light, there are no rods and cones. This part, the optic disk, cannot appreciate light, and hence is called the " blind spot." This fact shows that the nerve fibres are quite insensitive to light, and that we must look to the terminals for its appreciation.


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