A New Type of Hereditary Brachyphalangy in Man
A New Type of Hereditary Brachyphalangy in Man
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Flies homozygous for Star die without exception.
The mutant character Star, here chosen as an example, is not unique in this respect. In fact, 5 of the known 9 dominant mutants in Dro- sophila are completely lethal when homozygous, 1 is semilethal, and only 3 are not lethal when homozygous (Muller, 1917). Another well- known example is the yellow body-color in mice (Cue"not, 1915, 1918; Castle and Little, 1910).
Just as Star in Drosophila, so the brachyphalangy here described is of no practical... importance at all in heterozygous individuals. But it 46 A NEW TYPE OF BRACHYPHALANGY IN MAN.
is well worth noticing that in the single case where the possibility for homozygous individuals was present in our material, a child, 115. 2 9 C. F. H. , was born who was a cripple " without fingers and toes" and " with her whole osseous system in disorder. " As described above (pp. 28-29), this individual was unable to develop and died when one year old. The possibility that we are here dealing with a homozygous individual is pointed out above.
What to read after A New Type of Hereditary Brachyphalangy in Man?
You can find similar books in the "Read Also" column, or choose other free books by Otto L Mohr to read onlineMoreLess
To quickly assess the difficulty of the text, read a short excerpt:
Flies homozygous for Star die without exception.
The mutant character Star, here chosen as an example, is not unique in this respect. In fact, 5 of the known 9 dominant mutants in Dro- sophila are completely lethal when homozygous, 1 is semilethal, and only 3 are not lethal when homozygous (Muller, 1917). Another well- known example is the yellow body-color in mice (Cue"not, 1915, 1918; Castle and Little, 1910).
Just as Star in Drosophila, so the brachyphalangy here described is of no practical... importance at all in heterozygous individuals. But it 46 A NEW TYPE OF BRACHYPHALANGY IN MAN.
is well worth noticing that in the single case where the possibility for homozygous individuals was present in our material, a child, 115. 2 9 C. F. H. , was born who was a cripple " without fingers and toes" and " with her whole osseous system in disorder. " As described above (pp. 28-29), this individual was unable to develop and died when one year old. The possibility that we are here dealing with a homozygous individual is pointed out above.
What to read after A New Type of Hereditary Brachyphalangy in Man?
You can find similar books in the "Read Also" column, or choose other free books by Otto L Mohr to read onlineMoreLess
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