A Review of the Early Vaccination Controversy With An Original Letter By Jenner

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A Review of the Early Vaccination Controversy With An Original Letter By Jenner
Philip King Brown
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Dr. Woodville alone subjected nearly 4, 000 vaccinated patients to the small-pox inoculation in the course of six months and found that everyone of them resisted the infection. That experiment was re- peated probably not less than a million times, ac- cording to Willan and others, with the same re- sult. Cow-pox, therefore, is confessedly a pre- ventive of small-pox ; and the only question is whether it will be an infallible and a permanent preventive. The arguments on this point are of deep in...terest to us in light of our present vastly greater knowl- edge of immunity. "It seems contrary to all analogy, and all rules of reasoning, to suppose a priori, that an immunity which is found to subsist for a certain time in the usual and healthful state of the system, will grad- ually and insensibly wear away without any ap- parent cause, or any sensible change to indicate its extinction; and the facts which bear at all upon the question, so far from suggesting or supporting such a supposition, seem, in our apprehension, com- pletely to refute and discredit it.

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