A Study of the Bacteriology And Pathology of Two Hundred And Twenty Fatal Cases
A Study of the Bacteriology And Pathology of Two Hundred And Twenty Fatal Cases
W T William Thomas Councilman
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The average duration of the 14 cases in which they occurred was 17 days. The necrosis and abscess formation was due to infection through the bronchi. The foci seemed in some cases to begin as terminal foci similar to the foci of pneumonia in other cases, though extension through the walls of the bronchi could not be excluded. In some cases there were sharply circum- scribed areas of necrosis, involving but a few of the air spaces of an acinus. In the same cases there was found necrosis of the b...ronchial wall and of the adjacent air spaces. There was little or no inflammatory reaction around the necrotic tissue, and both the air spaces and walls were so filled with masses of diphtheria bacilli as to appear under a very low power as brightly stained areas. In other cases the tissue was partially broken down and necrotic, and filled with degen- erated pus cells and red blood corpuscles. In one of these cases, in the midst of the necrotic material, there were small islands of tissue, generally around the larger vessels, which were well preserved and infiltrated with pus cells.
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