A Treatise On Mental Diseases

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Some will show great congestion of the integument, dilated pupils, congested conjunctives, and dry throat, with mental distress, after the single administration of a quarter of a grain of the extract, while in others it takes doses of several grains, repeated at intervals of a few hours, to induce any constitutional effect. Even the application of atropine to the conjunctivas for any length of time may induce acute insanity, as in the following instance : A frail young girl of twenty -two years... had been ordered atropine drops to produce mydriasis for an ophthalmoscopic examination. She sud- RARER FORMS OF INTOXICATION 3Q3 denly developed indications of collapse, with hallucinations of sight and hearing, the insanity lasting nearly three weeks, several days after the last vestige of the effect of the atropine had disappeared from the eyes. Five years have elapsed since the attack, but there has been no repetition of the mental disturbance.
The mental symptoms of belladonna poisoning are of a more active character than that usually seen from any substances used in the medicinal treatment of disease, alcohol excepted.


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