An Introduction to the Study of Biological Chemistry

Cover An Introduction to the Study of Biological Chemistry
An Introduction to the Study of Biological Chemistry
Samuel Barnett Schryver
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tissues, and the group of substances containing phosphorus, known as the phospholipins, of which lecithin and the various brain lipoids, such as cerebrone, are examples.
Cholesterol, C 27 H 46 0, a monohydroxy alcohol, melting point 148-5-150'8, is the chief constituent of certain forms of gall-stones. It and its hydroxy derivatives are found in the majority of tissues. Its constitution is com- plex, and is still unknown. It can best be prepared in quantity from brains. The latter are dried by
...mixing with plaster of Paris, and the powder thus formed is ground up with sand. On extracting this mixture with cold acetone, and evaporating the extract, almost pure cholesterol separates.
Lecithin was originally prepared from yolk of egg. It yields on hydrolysis fatty acids, glycero-phosphoric acid, and choline. The constitution which has been assigned to it is the following : CH 2 -OCOC 17 H 35 JH-0 CO C 17 H 35 (or some other fatty acid radicle) P(OH) OCH 2 CH 2 N(CH 3 ) 3 OH II Such a product on complete hydrolysis would yield glycerol, fatty acids, phosphoric acid, and the basic substance choline, OH-CH 2 -CH 2 -N(CH 3 ) 3 OH, which on heating in aqueous solution decomposes into ethylene glycol (p.


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