An Introduction to the Study of the Endocrine Glands And Internal Secretions La
An Introduction to the Study of the Endocrine Glands And Internal Secretions La
Edward Albert Sharpey Schfer
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The former was prepared from thyroid by Baumann (1895) and found by him to con- tain a marked amount of iodine (. 3 to . 9 per mille of dry substance). In confirmation of this view the experiments of Reid Hunt and others seemed to show that the production of the autacoid is promoted by ad- ministration of iodides and that there is a certain relation between the physiological activity of the gland and its iodine content. But the fact that even when the dessicated thyroid contains a considerable ...amount of iodine it is sometimes found to have no action suggests that Baumann 's substance is not the actual autacoid, although it may be associated with it. We are in fact still in the dark so far as the true nature of this autacoid is concerned and it seems better to express our ignorance by a term which implies no theory, leaving the question of its identity with iodo-thyrin or iodo-thyro-globulin open. I propose therefore provisionally to apply the word thyrine to denote the active principle, whether it be identical with or contained in the iodo-thyrin of Baumann or not.
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