Bacteriology for Nurses Isabel Mcisaac

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Bacteriology for Nurses Isabel Mcisaac
Isabel Mcisaac
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" The chemical nature of tetanus toxin is not posi- tively known, but it is one of the most powerful poisons known.
Tetanus Antitoxin or Antitetanic Serum. The principles involved in the production of an antitoxin in diphtheria are identical in tetanus ; in fact, it was through the researches into tetanus that the prin- ciples were first worked out.
Animals are immunized from tetanus by the TETANUS 133 repeated injection of gradually increasing doses of tetanus toxin, until the blood contains t
...he required amount of antitoxin; the blood-serum of the immune animal is capable of protecting the susceptible animal or human from the action of the tetanus toxin and also against the effects of the living tetanus bacillus.
The use of the tetanus antitoxin for the treatment of tetanus has been far less successful than the use of diphtheria antitoxin for diphtheria, because in diphtheria the local signs in the throat lead to an early diagnosis and treatment before the bacilli have produced an overwhelming amount of toxin; while in tetanus the first symptoms are the convul- sions which are due to the presence of the toxins.


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