Chemistry of the Albumens Ten Lectures Delivered in the Michaelmas Term 1904

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These processes are gener- ally repeated several times. The formula of haematine has not yet been determined with certainty. It is probably either C M H 3 AN 4 Fe, which can be derived from haemine according to the equation C 34 H 33 4 N 4 ClFe + NaOH = NaCl + C 34 H 34 O 5 N 4 Fe, or C 34 H 32 5 N 4 Fe, derived according to the equation C 3 4 H 33O 4 N 4 ClFe + NaOH + O = C 34 H 32 O 5 N 4 Fe + H 2 O + NaCl.
It is almost certain that haematine is produced from haemine by the replacement of chl
...orine by a hydroxyl group; the former is not merely a hydrochloride of the latter.
Dehydrochloride of famine. It has been stated above that in the Schalfejew method of purifying haemine by treatment with pyridine or quinine in chloroform solution, a scission of hydro- chloric acid takes place ; on pouring the basic chloroform solution into acetic acid containing hydrochloric acid, readdition * The general results of Kiister have since been confirmed by Hetper and Marchlewski.
128 THE CHEMISTRY OF HEMOGLOBIN [LECT.


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