Clinical Hematology a Practical Guide to the Examination of the Blood With Ref

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Clinical Hematology a Practical Guide to the Examination of the Blood With Ref
John Dacosta
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Of the above-named changes the most important, from a cHnical viewpoint, is the prevalence of nucleated erythrocytes conforming to the megaloblastic type. With the two exceptions already noted (bothriocephalus anemia and nitrobenzol poisoning), this ''mega- loblastic blood-picture" is seen only in pernicious anemia, and, what is more important, it occurs in every true case of this dis- ease sooner or later during its course. Inability to detect this important characteristic should be regarded r...ather as a reflection upon the thoroughness of the examiner's technique than as a contradiction of the truth of this statement. Eiythroblasts ^me not always numerous in pernicious anemia, and painstaking^avity prolonged study of several stained films may be necessary ' this important feature is distinguishable. General In those cases of doubtful nature, in which the typicao-es the changes are not at once evident, a tentative diagnosis as com- made by taking into careful consideration certain other ) that the signs and symptoms which the patient presents.

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