Contributions From the University Laboratory for Medical Bacteriology to Celebrate the Inauguration of the State Serum Institution

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Little by little the most accessible alkali or lysin-bound corpuscles are haemolysed, and later on the most resistent, whose membranes will be destroyed only after a prolonged action of the toxin. In chemistry several similar phenomena occur, especially when solu- tions act upon solid bodies; and it is then said, that a certain time of induction is necessary, before the attack occurs. Physicists often find it difficult to understand what this time of induction means. In the present case it is e...asily explained why there should be a time of induction, this being here equivalent to the time requi- red for the destruction of the cellular membrane.
In order to clear up the connection between the con- centration of toxin and the velocity of reaction, we must therefore proceed so that we ascertain if a certain dose of toxin produces the same degree of haemolysis during a certain time as half that dose of toxin effects in double that time. From the above figures this would seem to — 28 — Ill be, roughly speaking, the case.


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