Diseases of Children Designed for the Use of Students And Practitioners of Medi

Cover Diseases of Children Designed for the Use of Students And Practitioners of Medi
Diseases of Children Designed for the Use of Students And Practitioners of Medi
Herman Bernard Sheffield
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In malignant cases or in those seen late, double doses should be adminis- tered at once and, if necessary, repeated, or the antitoxin may be ad- ministered intravenously (after warming the antitoxin in its container in hot water). The effect of the serum is very beneficial, nay, sometimes magical. After a temporary rise, the fever often falls by crisis, the pulse improves, the membranes loosen and disappear, and the whole as- pect of the case sometimes changes completely for the better, within ...from eighteen to twenty-four hours. However, notwithstanding all that was said in favor of the antidiphtheritic serum, it is not always advisa- ble to depend upon the serum alone.
As diphtheria is originally a local affection and the secretion and ab- sorption of the metabolic products (toxins) occur from the local lesion, the urgency of the immediate destruction of the bacilli at their point of entrance is self-evident. This is best accomplished by the different germicides and solvents, such as peroxide of hydrogen, strong solu- tions of carbolic or salicylic acid, 20 per cent to 50 per cent solutions of resorcin in alcohol, tincture iodine, argyrol or solargentum (20 per cent), or the carbol-camphor solution referred to on p.


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