Diseases of Children Designed for the Use of Students And Practitioners of Medi
Diseases of Children Designed for the Use of Students And Practitioners of Medi
Herman Bernard Sheffield
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In malignant cases or in those seen late, double doses should be adminis- tered at once and, if necessary, repeated, or the antitoxin may be ad- ministered intravenously (after warming the antitoxin in its container in hot water). The effect of the serum is very beneficial, nay, sometimes magical. After a temporary rise, the fever often falls by crisis, the pulse improves, the membranes loosen and disappear, and the whole as- pect of the case sometimes changes completely for the better, within ...from eighteen to twenty-four hours. However, notwithstanding all that was said in favor of the antidiphtheritic serum, it is not always advisa- ble to depend upon the serum alone. As diphtheria is originally a local affection and the secretion and ab- sorption of the metabolic products (toxins) occur from the local lesion, the urgency of the immediate destruction of the bacilli at their point of entrance is self-evident. This is best accomplished by the different germicides and solvents, such as peroxide of hydrogen, strong solu- tions of carbolic or salicylic acid, 20 per cent to 50 per cent solutions of resorcin in alcohol, tincture iodine, argyrol or solargentum (20 per cent), or the carbol-camphor solution referred to on p.
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