Experimental Investigations With Trypan Blue in Connection With the Intraspinal
Experimental Investigations With Trypan Blue in Connection With the Intraspinal
Jacob Goudsmit
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Gonorrhoea, no syphilis. Neurological Examination: Tremors in hands and legs, especially on the right side. Hypalgesia of the whole body; the upper part of the back proves to be analgetic. Disturbance in the deep sensibility of the legs. Ataxia. Gait: atactic. Romberg's sign is positive. The pupils are equal, do not react to light. Good reaction to accom- modation. Absence of knee and ankle-jerks. Psychical state: Retention and memory show defects. Cerebrospinal fluid: Wassermann R. 9/10 Nonne ...+ Pleocytosis 42 Blood: Wassermann test 8/10 112 23-7-' 17: Patient is treated with intravenous injections of neosalvarsan. Within 7 weeks 4500 m. Gr. Are injected intravenously. 26-9-' 17: The incontinence of urine is increasing quickly; the ataxia of the gait also increases. 31-10-'17: The psychical state inclines to get worse: patient loses his sense of judgment and shows typical megalomania. 7-1 1-' 17: Intraspinal injection of l 1 / m. Gr. Of neosalvarsan. 8-ll-'17: Temperature is 38. 2 C. 13-11-'17 Intraspinal injection of 2 m.
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