Genentech Legal Counsel And Vice President 1976 1988 And Entrepreneur Oral H

Cover Genentech Legal Counsel And Vice President 1976 1988 And Entrepreneur Oral H
Genentech Legal Counsel And Vice President 1976 1988 And Entrepreneur Oral H
Thomas D Kiley
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Hughes: Oh, really?
Kiley: Now, for twenty years I ve been involved in biotechnology patent law and practice, and I haven t prepared a patent application in all that time. But I did weigh in from time to time when applications prepared by others needed to be pushed over the goal line, most notably in the tPA [tissue plasminogen activator] case and the interferon gamma case.
Gamma Interferon Hughes: What do you mean by "pushed over the goal line?" 60 Kiley: Well, 111 illustrate with reference to
... interferon gamma. Genentech announced the cloning of interferon gamma, and just before it did, Genentech filed a patent application for what it believed to be the sequence of DNA that encodes interferon gamma. It turned out the inventors had guessed wrong as to the start point for the DNA and the corresponding amino acid sequence, with the result that what was first described, both in the publication and in the patent application in so many terms, was not interferon gamma, but interferon gamma with extra amino acids at its N-terminus-cystine, tyrosine, cystine.

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