Handbook of Physiology

Cover Handbook of Physiology
Handbook of Physiology
W D William Dobinson Halliburton
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. 0'042 Calcium chloride . . . 0'048 Sodium bicarbonate . . . . 0'02, Dextrose . . 0'2 Dr Locke has tried other sugars besides dextrose, but no other has the same favourable effect ; Isevulose is better than most other sugars, but not nearly so good as dextrose. Locke and Rosenheim have further shown that the dextrose is used up during cardiac activity, and this lends support to the view already expressed on the importance of this kind of sugar as a source of muscular energy (see p. 131).
A mam
...mal such as a cat or rabbit is killed by bleeding or pithing. The heart enclosed in the pericardium is quickly cut out, and gently kneaded to free it from blood, in some warm Einger's solution. The pericardium is then dissected off, and a cannula tied into the aorta; this is connected to a burette which is kept full of Locke's solution. The solution must be maintained at body tempera- ture, by a warm water-jacket, and must be well oxygenated by letting oxygen bubble through it. The fluid is then allowed to flow, and its pressure closes the aortic valves, and so the fluid enters the coronary arteries, and escapes from the right auricle, which should be freely opened.

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