Immune Sera a Concise Exposition of Our Present Knowledge Concerning the Consti
Immune Sera a Concise Exposition of Our Present Knowledge Concerning the Consti
Charles Frederick Bolduan
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That the serum or 152 APPENDIX. spinal fluid contained syphilis antibody. As in most such tests, only a positive result determines ; a negative result does not necessarily exclude the presence of syphilitic infection. While the above exposition will serve to fix the general plan of the test in the mind of the reader, we must at once say that the mode of action is not as simple as Wassermann first believed. Before going into this phase of the subject, it will be advisable to present a descriptio...n of the technique of the test. For carrying out the test the following materials are required: (1) Antigen, i. E. Fluid containing syphilis ma- terial. This is comparable to the pure culture of typhoid in the test described above. (2) Serum or cerebrospinal fluid from the patient to be examined. (3) Sheep blood cells. (4) Hasmolytic antibody, i. E. Inactivated serum of a rabbit immunized against sheep blood cells. (5) Complement, i. E. Fresh normal serum from a guinea-pig. For the syphilis antigen it is best to use the organs of a syphilitic fcetus, i.
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