Immune Sera a Concise Exposition of Our Present Knowledge of Infection And Immu
Immune Sera a Concise Exposition of Our Present Knowledge of Infection And Immu
Charles Bolduan
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Agglutinins can also be developed against red blood cells and against certain protozoa (trypan- osomes). We speak of the former as hamag- glutinins. Analogous to the haemolytic action or normal serum on the red cells of certain other species, we find that normal serum is able to agglutinate the red cells of many species and bac- teria. For example, normal goat serum aggluti- nates the red cells of man, pigeon, and rabbit; normal rabbit serum agglutinates typhoid and cholera bacilli. Of practica...l interest is the fact that normal serum may agglutinate the red blood cells of another indi- vidual of the same species. Following Ehrlich's nomen- clature, we speak of this as is o agglutination. The subject has been studied by a number of investigators, and mostly in human blood. According to the extensive investigations of Moss, isoagglutinins occur in the serum of about 90% of adult human beings. Landsteiner divided the individuals into three groups, namely : Group i. The corpuscles are not agglutinated by sera of the other two groups, while the sera agglu- tinate the corpuscles of both groups.
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