Infection And Resistance; An Exposition of the Biological Phenomena Underlying the Occurence of Infection And the Recovery of the Animal Body From Infectious Disease
Infection And Resistance; An Exposition of the Biological Phenomena Underlying the Occurence of Infection And the Recovery of the Animal Body From Infectious Disease
Hans Zinsser
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After these materials had been together for a certain time, sensitized red blood cells were added. If the complement was bound during the first exposure no hemolysis resulted and the reaction was regarded as positive. From their results they drew the following conclusions : 1. Immune serum from monkeys, produced by treatment with syphilitic material, will sensitize syphilitic material from human beings or monkeys, so that an alexin-fixing complex is formed. 2. Complement fixation results only w...hen the syphilitic immune serum of monkeys is added to similar material from men or mon- keys, but not when added to organ extracts of normal men or mon- keys. 3. Xormal monkey serum has no such action. They concluded that their results justified them in asstmiing a specific fixation due to specific antisyphilitic immune bodies in the blood of the treated monkeys. They excluded experimentally the possibility of fixation by a precipitin reaction resulting from the treatment of the monkeys with human material.
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