Infection Immunity And Serum Therapy in Relation to the Infectious Diseases O

Howard Taylor Ricketts

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If they were identi- cal, immunization with the one would yield an ag- glutinating serum of equal power for both cells; this, however, is not the result obtained. On the other hand, the agglutinins of two different organ- isms may coincide to a certain degree, as will be shown under the subject of "group agglutination. " Certain experiments go to show that the agglutin- ogen of even a single micro-organism is not uni- form substance. One portion is heat-susceptible, being destroyed at 62 C. , w...hile another portion is said to resist a temperature of 165 C. Such tech- nical questions continue to be investigated.
Agglutinogens are said to pass through semi- Fiageiiar permeable membranes, while agglutinins do not.
Smith and Eeagh distinguish two kinds of ag- glutinogen in those bacteria which possess flagella, one peculiar to the cell body, and the other to the flagellae.
Agglutinin may be precipitated completely from a serum by the sulphates of magnesium or ammo- nium, when the salts are used in proper concentra- tions.

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