Lectures On Tropical Diseases Being the Lane Lectures for 1905 Delivered At Co
Lectures On Tropical Diseases Being the Lane Lectures for 1905 Delivered At Co
Patrick Manson
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Keep a register of the number of filarise you find in each sample of blood. Keep on doing this for a week, a month, a year, taking care meanwhile that the man is in good health, and that he observes normal habits as regards the hours of sleeping and waking. You will very soon satisfy your- self that the filaria exhibits a very definite periodicity as regards its presence in the peripheral circulation. You will find that it is present in enormous numbers perhaps three or four hundred per drop at... midnight ; that FILARIASIS. 71 it is practically absent at midday ; that it begins to put in an appearance about six or seven in the evening, gradually increasing in numbers up to about midnight, and gradu- ally decreasing in numbers up to about seven or eight in the morning ; and that it is almost entirely absent from eight or nine a. M till about six or seven p. M. The question is often asked, what becomes of the embryo filaria during its temporary absence from the peripheral circulation during the day ?
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