New Hydroxamic Acids Derived From Cyclopropane Carboxylic Acid Isobutyric Acid
New Hydroxamic Acids Derived From Cyclopropane Carboxylic Acid Isobutyric Acid
Alfred Witherspoon Scott
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After evaporation of the alcohol, a viscous semi-solid mass resulted. This mass was dissolved in water and treated with a solution of copper acetate. A grass-green copper salt of the hydroxamic acid was precipitated ; it was collected, washed thoroughly with water and dried over sulfuric acid. When the dry copper salt had been pulverized carefully, it was suspended in methanol and a stream of dry hydrogen sulfide was passed through the suspension. The solution was filtered from copper sulfide a...nd the methanol evaporated. The product was a yellowish crystalline material possessing an odor characteristic of impure hydroxamic acids prepared from their copper salts by this method. Upon recrystallization of it from warm ethyl acetate, pure cyclopropane-monocarboxylic hydroxamic acid was obtained; it melted at 124 with decomposition. When ligroin is 415 added to the ethyl acetate solution, some of the yellow impurity is precipitated together with a part of the hydroxamic acid. Analyses. Subs.
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