On the Relative Efficienty of the Various Methods of Administering Saline ...

Frank Watts Bancroft

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In all the ex- periments the controls never once showed such a regular increase in the fluidity of the feces. These facts show very conclusively that the intravenous injection of sodium sulphate increases markedly the amount of water in the feces.
COMPARISON WITH ADMINISTRATION BY MOUTH.
When now we come to compare the effect of giving sodium sul- phate by mouth with the results just described, a decided differ- Digitized by Google 202 Saline Purgatives cnce is observed. Fluid feces can easily ...and almost invariably be obtained by giving sodium sulphate by mouth. From 60 to no cc. of y sodium sulphate or 250 to 300 cc. of the ^ solution caused an elimination of fluid feces in every case except one, and in no case had any injurious effect on the rabbit. Why this differ- ence? In answering this question it is essential that the normal anatomy and physiology of the rabbit* s digestive tract should be kept in mind. The food is ordinarily very bulky, containing much cellxilose, and the digestive tract is adapted to these conditions.

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