Phenylketonuria : a Selected Bibliography
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Jervis, George A.: Genetics of Phenylpyruvlc Oligophrenia. JOURNAL OF MENTAL SCIENCE, 1939, 85> 719-762 (July) .
The paper presents a genetic study of 200 cases of phenylpyruvlc oligophrenia. Environmental and hereditary factors are discussed.
In conclusion, the data are consistent with the quantitative re- quirements of the theory of monomeric recessivity, since (a) the ratio of affected to normal sibs In families with normal parents, when corrected by specific method of statistical analysis, ...is found to be 25 percent; (b) the rate of consanguinity among the parents of affected individuals is significantly higher than normal; (c) the distribution of the character among ascendant and collateral relatives follows the rules of monomeric recessivity. Phenylpyruvlc oligophrenia, therefore, appears to be a clear Illustration of a type of mental deficiency determined by a single autosomal reces- sive gene.
Jervis, George A.: Detection of Heterozygotes for Phenylketonuria.
CLINICA CHIMICA ACTA, I96O, S, 47I-U76 (July).
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To quickly assess the difficulty of the text, read a short excerpt:
Jervis, George A.: Genetics of Phenylpyruvlc Oligophrenia. JOURNAL OF MENTAL SCIENCE, 1939, 85> 719-762 (July) .
The paper presents a genetic study of 200 cases of phenylpyruvlc oligophrenia. Environmental and hereditary factors are discussed.
In conclusion, the data are consistent with the quantitative re- quirements of the theory of monomeric recessivity, since (a) the ratio of affected to normal sibs In families with normal parents, when corrected by specific method of statistical analysis, ...is found to be 25 percent; (b) the rate of consanguinity among the parents of affected individuals is significantly higher than normal; (c) the distribution of the character among ascendant and collateral relatives follows the rules of monomeric recessivity. Phenylpyruvlc oligophrenia, therefore, appears to be a clear Illustration of a type of mental deficiency determined by a single autosomal reces- sive gene.
Jervis, George A.: Detection of Heterozygotes for Phenylketonuria.
CLINICA CHIMICA ACTA, I96O, S, 47I-U76 (July).
What to read after Phenylketonuria : a Selected Bibliography?
You can find similar books in the "Read Also" column, or choose other free books by United States. Children's Bureau to read onlineMoreLess
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