Poisons Their Effects And Detection By Alexander Wynter Blyth And Meredith Wyn
Poisons Their Effects And Detection By Alexander Wynter Blyth And Meredith Wyn
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A second alkaloid, ^ Die thierischen Gifte, Braunschweig, 1906. 492 §§ 644-646-] POISONOUS AMPHIBIA. 493 (<-'2oH3iNO)2 + H2S04, was obtained by Faust, the sulphate of which is less soluble than that of samandarin ; to this he gives the name of Samandaridin sulphate. It is optically inactive. The crystals are in the form of rhombic plates or tables. There is more samandaridin to be obtained from the salamander than samandarin, the proportion being about 2 to 1. On dry distillation with zinc dust an alkaline distillate is obtained, from which Faust isolated isochinolin ; the same author states that the more 'volatile constituents of the decomposition give the reactions of pyrrol. With regard to the chemical relationship between the two alkaloids, Faust suggests that samandarin possesses one more methyl-pyridin group, CVHglCHgjN, than samandaridin. § 644. Poisoning by the samandarins produces symptoms strikingly similar to those of rabies, in all its three stages— viz. The excitable stage, with exaltation of the reflexes, restlessness, acceleration of the respira- tion, dilatation of the pupil, and increase of the nasal and buccal secretions; next, the convulsive stage, with catching respiration, dyspnoea, and convulsions ; and, lastly, the paralytic stage ending in death, the cause of death usually being paralysis of the respiratory centre.
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To quickly assess the difficulty of the text, read a short excerpt:
A second alkaloid, ^ Die thierischen Gifte, Braunschweig, 1906. 492 §§ 644-646-] POISONOUS AMPHIBIA. 493 (<-'2oH3iNO)2 + H2S04, was obtained by Faust, the sulphate of which is less soluble than that of samandarin ; to this he gives the name of Samandaridin sulphate. It is optically inactive. The crystals are in the form of rhombic plates or tables. There is more samandaridin to be obtained from the salamander than samandarin, the proportion being about 2 to 1. On dry distillation with zinc dust an alkaline distillate is obtained, from which Faust isolated isochinolin ; the same author states that the more 'volatile constituents of the decomposition give the reactions of pyrrol. With regard to the chemical relationship between the two alkaloids, Faust suggests that samandarin possesses one more methyl-pyridin group, CVHglCHgjN, than samandaridin. § 644. Poisoning by the samandarins produces symptoms strikingly similar to those of rabies, in all its three stages— viz. The excitable stage, with exaltation of the reflexes, restlessness, acceleration of the respira- tion, dilatation of the pupil, and increase of the nasal and buccal secretions; next, the convulsive stage, with catching respiration, dyspnoea, and convulsions ; and, lastly, the paralytic stage ending in death, the cause of death usually being paralysis of the respiratory centre.
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