Principles of Immunology

Cover Principles of Immunology
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Here, he asserts, bac- teriolysis and phagocytosis progress actively. Hence the disappearance of the cells from the exudate.
A similar experiment may be performed with a suspension of pigment, as for example 5.0 c.c. finely-divided suspension of cinnabar (red mercuric oxide).
This shows no digestion but active phagocytosis and a rapid transfer to re- gional lymph-nodes.
Phagocytosis of bacteria may be very well demonstrated with colon bacilli.
It is desirable in this instance to excite some exu
...dation before the introduction of the colon bacilli. This may be produced by injecting about twelve hours previously 10.0 c.c. sterile bouillon or aleuronat suspension. This may be done in the evening and the following morning the guinea-pig is ready for the injection of a 24-hour bouillon culture or a 24-hour slant agar culture suspended in salt solution. The subsequent phenomena are similar to those following the injection of bird blood.
The Mechanism of Phagocytosis. — In earlier experiments of this sort several questions as to the mechanism of the process arose.


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