Recent Biochemical Investigations On Blood And Urine Their Bearing On Clinical

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Take the nonprotein nitrogen and urea, for example. There is no doubt, I think, that in case of strictly normal persons such as we find among medical students (or outside of hospitals), the nonprotein nitrogen content and urea content of blood are low. The nonprotein nitrogen will not exceed 28, or at the most 30 mg. Per hundred c. C. Of blood, -and the urea nitrogen will be almost exactly one half of the non- protein nitrogen. Nor are these levels materially affected by reasonable variations i...n the nitrogen con- tent of the food. To me it seems a matter of con- siderable significance that we have to accept as normal considerably higher levels just as soon as we begin to work on hospital patients. Here values lying between 30 and 40 dre quite as common as values under 30. There can be no doubt about the fact that efficiency of the kidneys is the chief factor which determines the level of waste products which any individual carries in his blood and tissues. The higher levels of waste products found among hospital patients must therefore indicate that at least one half of these persons have kidneys which are no longer perfect, kidneys which at one time or another and in one way INVESTIGATIONS ON BLOOD AND URINE 13 or another have been damaged.

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