Special Pathology And Therapeutics of the Diseases of Domestic Animals

Cover Special Pathology And Therapeutics of the Diseases of Domestic Animals
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On the other hand, injections of the ?anie doi^es made subcutaneously resulted in lesions confined to the area of injection. Administration of the same virus by the way of the alimentary canal to animals previously imnmnized resulted in rather extensive affec- tion of the tonsils. Similar results were obtained not only with Behring's original bovo-vaccine but also with culture of human tulierele bacilli 4 to 6 weeks old. When the resistance of the vaccinated animals was tested 7t^ and 17 months... later the con- trol infections resulted in extensive and partly in fatal general tuberculosis.
Eber tested the resistance of four animals immunized by Behring's method by repeatedly exposing them to animals with experimental tuberculosis. Two years later, when they were slaughtered they were without exception found to be affected Avith focal tuberculosis of a more extensive nature than that affecting the control animals.
In exjieriments conducted with 20 vaccinated animals by Eossignol & Vallee in Melun, with the same numlier of controls, while giving gratifying results three months later when 13 animals of each group were subjected to control infection, iurther observation disclosed that two of the vaccinated animals became tuberculous and another died within 50 days from the effects of subsequent intravenous infection.


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