The Action of Various Pharmacological And Other Chemical Agents On the Chromatophores of the Brook Trout Salvelinus Fontinalis Mitchill

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The ganglion free heart did not re- spond to the poison. Plateau C78) observed a primary stimu- lation in the heart of Carcinus moenas and Homarus (sp.) which was followed by a depression. Romanes ('77) found- that in the medusa Sarsia (sp.) the first effect of veratrine was an increase in the number and potency of the contractions. This period of increased responsiveness was followed by a gradual depression into complete quiescence.
Summarizing the action of veratrine on the pigment cells, it
...may be stated, that it first stimulates the contraction of the pigment cells. This period of stimulation is followed later by a paralysis of the mechanism controlling the pigment cells. The pigment cells are expanded during this period of depression.
This is in harmony with the observations of other workers on various tissues, where there is observed a primary stimulation followed by a depression.
10. Quinine. Quinine in a 0.5 per cent maintained for a long time the pigment cells in an expanded condition.


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