The Department of Biochemistry And the Molecular Approach to Biomedicine At the
The Department of Biochemistry And the Molecular Approach to Biomedicine At the
W J William J Rutter
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Did Wally Gilbert have those responsibilities? No. So it was a complex situation. I considered my departmental duties to be very a significant personal obligation. It was a complex life for me, for sure. As department chairman, I also had to deal delicately with the issues of competition within the department, especially when I was involved. Did you feel that you were in competition with Howard Goodman? Yes, for sure. If he was going to do the same thing as I was going to do, then we would be r...eally in competition. I learned that Howard had already talked with Jerry Grodsky who was in the [UCSF] Metabolic Research Unit. Jerry Grodsky also had worked on the preparation of islet cells that could be used as a source for the gene. But Jerry had no experience in biochemistry and genetics. Hence bringing in Jerry would have made a tenuous three-way partnership. So I talked it over with Howard. Pictet had had much more experience than Jerry in purifying islet cells. Furthermore, we had done a lot of work on the isolation of those fish islet cells and on the development of a process for destroying the RNase.
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