The Essentials of Clinical Toxicology

Cover The Essentials of Clinical Toxicology
The Essentials of Clinical Toxicology
Louis C Chandler
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Usually slow. Internally it produces no effect like the external burning. Is non-corrosive and has no action until absorbed into the tissues. Death in less than 12 hours rare, and then due appar- ently to cardiac paralysis. Essential action is in- terference with internal oxidations of cells, re- sulting in the degeneration of those which are reached by any more than the merest traces of the drug. This explains the pathological condi- tions set up and the symptoms developed. Death usually due t...o severe metabolic disturbances or degenerations of vital structures, or of blood ves- sels, after disappearance of primary period of gas- tro-intestinal suffering. Most common time of death between second and seventh day.
Symptoms. First Period. May be taste of garlic at time of ingestion, followed by odor of garlic on breath. Both of these may be lacking.
71 Abdominal pain and Vomiting, after a period of from 2 to 6 hours after ingestion. (These are due to non-inflammatory changes in the gastro-intestinal mucosa, as the drug acts upon the cellular elements as it is ab- sorbed into them.


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