The Harmful Effects of Acetanilid Antipyrin And Phenacetin
The Harmful Effects of Acetanilid Antipyrin And Phenacetin
Lyman F Lyman Frederic Kebler
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A nervous patient, 35 years of age, took 10 grains of antipyrin and 3. 75 grains of hydrobromate of quinine. Purpuric spots appeared upon the palm, sole, and fingers, followed by desquamation. There was also redness of the urethra and glans, with discharge. CARDOSO, A. 17m casa de idiosyncrasia para a antipyrina. Med. Mod. , Porto, 1902, 9: 250. CROUZEL, E. Sur un case d'idiosyncrasie. J. Med. Bordeaux, 1902, 32: 794. Every time that the author took antipyrin, 3. 75 grains, there appeared on th...e dorsum of the left hand a red erytheuiatous patch, painful on pressure. 19O3. CLAVERIE. Eruption, erythemato-bulleuse due a 1'antipyrine. Rev. Med. 1'Afrique du nord, Alger, 1903, 6: 2228. Man. 72, headache: Six hours after the ingestion of 15 grains of anti- pyrin erythema-toils spots appeared all over the body, with the subsequent development of vesicles and bullre. DANLOS. Eruption a type d'erythme polymorphe produite par 1'antipyrine. Bui. Soc. Franc, dermat. Syph. , Paris, 1903, 14: 233. On two occasions the ingestion of antipyrin was followed by nervousness, insomnia, a skin eruption, and the development of blisters in the mouth and upon the genitals.
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