The Influence of the Pituitary Gland On Parturition

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TO INFLUENCE OF THE PITUITARY GLAND ON PARTURITION II. Metabolism Studies During Injections of Extracts of the Posterior Lobe of the Hypophysis.
In the first paper of this series (Morris 1 ) it was shown that the peculiar reaction of the animal body during parturition might be explained by the increased activity of the posterior lobe of the hypophysis. In the present paper a study has been made of the nitrogen metabolism after injections of pituitrin.
The major portion of the experimental work
...on pituitrin in- jections has been concerned with the anti-diuretic effect. Some slight variations occur according to the method of administration.
Given orally, or subcutaneously, an immediate physiological effect has not been noted, although Hamill 2 found that given by the mouth to cats in full digestion caused certain disturbances of the intestines and uterus. The effect on the urinary secretion also varies according to the mode of injection (Schafer 3 ). An intra- venous injection causes a marked diuresis immediately followed by a more prolonged anti-diuresis, and a subcutaneous injection causes anti-diuresis followed by a marked diuresis (Lebermann 4 ) .


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