The Journal of Infectious Diseases

Cover The Journal of Infectious Diseases
The Journal of Infectious Diseases
Infectious Diseases Society of America
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Kolmer and Allen J. Smith (y^ to I grain) each day for from 3 to 6 days represents a very high dilution of the drug in the body fluids of the patient, it is readily under- stood that emetin wields a very high and specific amebacidal action in vivo.
Similar results have been noted in the treatment of amebic dysen- tery and its complications, the success of the drug in the treatment of this disease having suggested its use in the treatment of amebic pyor- rhea.* conclusions Emetin hydrochlorid ad
...ministered intravenously to rabbits in doses varying from 0.065 to 0.52 gm. (1 to 8 grains) per 132 pounds of body-weight exerted slight or no antiseptic or germicidal influenc'e on a virulent culture of Staphylococcus aureus ; abscesses developed in the internal organs of the majority of experimental animals.
Emetin hydrochlorid administered intraperitoneally tg mice in doses varying from 0.065 to 0.52 gm. and 0.975 gm. (1 to 8 and 15 grains) per 132 pounds of body-weight exerted no appreciable inhibitory or germicidal action on anthrax and tetanus bacilli.


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