The Pathology of the Pneumonia in the United States Army Camps During the Winter of 1917-18

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WILLIAM G. MacCALLUM 91 In Case 56 there was a gross extension of the infection through the diaphragm so that an abscess-like accumulation of pus on the pleural surface communicated freely with a similar enclosed pocket on the upper surface of the liver.
The testes show in nearly all these cases an extraordinary change which is especially striking in the streptococcal infections, although occurring sometimes in the pneumococcal infection and failing to appear in some of the streptococcal ones.
...It appears to consist in a cessation of spermatogenesis which has probably come about through a stoppage of mitosis at an early stage. In most of the cases of streptococcal infection spermatozoa are not to be found in the tubules of the testis, although a few may persist in the seminal vesicles em- bedded in the viscous fluid which is found there. Not only are the spermatozoa absent, but in many cases one looks in vain for sperma- tids or spermatocytes. The spermatogonia are always present, and the Sertoli cells become very conspicuous, but with only these types of cells left the tubule is reduced to an extremely simple structure.

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