Therapeutics Its Principles And Practice

Cover Therapeutics Its Principles And Practice
Therapeutics Its Principles And Practice
H C Horatio C Wood
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Elaterium occurs in light, friable, slightly incurved, greenish- gray cakes about a line thick. The taste is acrid and bitter, the fracture finely granular. Owing to the variability of commercial elaterium, the U. S. Pharmacopoeia now recognizes only the active principle, Elaterin (ELATERINUM, U. S. ), which was first separated in a pure state by Mor- ries. 51 It crystallizes in colorless, shining, rhombic, six-sided, odorless tables, of a very bitter sharp taste and neutral reaction. PHYSIOLOG...ICAL ACTION. Locally applied, elaterium is a very de- cided irritant, producing, according to Pereira, ulcerations in the fingers of those who handle the fruit and prepare the drug for market. When taken internally, it acts on man as a most powerful hydragogue cathartic. On the lower animals its action is much less certain. Viborg asserts that a horse was unaffected by a pound of elaterium fruit ; and H. C. Wood has given one and even two grains of a presumably active elaterium to a dog without producing very obvious results.

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