Transactions of the ... Annual Session of the Medical Society of the State of North Carolina [serial] 34 (1887)

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From the obi-ervations of Frerichs and of Jones, we learn that the pathological changes of all forms of malarial fever are uniform, and consist essentially in "Diminution of colored blood corpuscles, deposit of pigment in liver and spleen and increased secretion of bile."J The composition and amount of urine was found to vary with stage, intensity and type of disease. Jaundice, bilious vomiting and dark brown or black urine was observed in the gravest cases.
From this brief historical allusion
...we are forced to conclude that Malarial Hematuria or Haimorrhagic Malarial fever is not a new disease, but its recognition as a distinct type is modern. The saraf- •-7'- symptoms and signs were recognized more than two thousand years ago, but only since 1866 or '67 has it been given so dignified a place as a separate and distinct type in the classification of diseases. It was / before that time considered a complication of other forms of favefe— /^ ' nevertheless, its essential characteristics were known to Greek, Roman and Arabian physicians.

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