Uric Acid As a Factor in the Causation of Disease: a Contribution to the ...

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Uric Acid As a Factor in the Causation of Disease: a Contribution to the ...
Alexander Haig
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Diagnosis. — ^The time has not yet arrived for dogmatising ; but where epileptic fits have recurred with more or less periodicity for a long time, and resemble migraine in their relation to dyspepsia, muscular exertion, or menstruation ; where they are accompanied by scanty urine, and preceded by a slow and faltering pulse, with altered capillary circulation ; when also there is no syphilis or other organic cause, I suggest that they may be due to the efifects of uric acid on the circulation in
... the skull or on the action of the heart, and that further investigation or treatment from that point of view is indicated.
The Indications for Treatment are much the same as in migraine.
An attempt may be made to break through the fits, or the attendant stupor and headache, by the use of such drugs as acids, calomel, morphine or the nitrites, with or without temporary compression of the carotid.* * For oases where this was done, see Lancet^ 1892, vol. i., p. 358, and vol. ii., 662.
Digitized byLjOOQlC 298 UBIC ACID — CHAPTBB VII I have seen many cases where aoids relieved the stupor and headache that follow the fits, and in some the patients would ask for their dose as they regained consciousness.


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