Uric Acid : the Chemistry, Physiology And Pathology of Uric Acid And the Physiologically Important Purin Bodies, With a Discussion of the Metabolism in Gout

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Chemie, 1, 218 (1853).
*L. Meyer. Die Gase des Blutes. Zeitsohr. f iir rationnelle Med. NeueFolge, 8, 256 (1857).
5 E. Munzer und P. Palmer. Ueber den Stoffwechsel des Menschen bei Kohlendunst- und Nitrobenzolvergiftung. Zeitschr. fiir Heilkunde, 15, 1 (1894).
^ H. Jacubasch. Beitrage zur Harnanalyse bei lienaler Leukamie. Virchow's Archiv, 43, 196 (1868).
Physiology 169 cient oxidation. Mosler did not find the uric acid excreted always increased in leukemia/ and came to the conclusion that thi
...s in- creased excretion occurred only when with the leukemia there was at the same time a relatively insufficient supply of oxygen to the tissues.^ A further apparent confirmation of Bartels' theory was seen in the work of Kollmann,^ Eckhardt/ and Sticker.^ These authors found that the high uric acid in leukemia and emphysema, which was explained as due respectively to deficient internal and ex- ternal respiration, could be decreased by oxygen inhalation. The work of J. Ranke^ and others who found the uric acid in the urine, like the urea, dependent on the proteid of the diet, was considered another confirmation of the theory that uric acid comes from proteid.

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